Fast economic growth puts a pressure cooker on a region's capacities to accomodate the challenges which come along with this, in itself, very positive change. Provide housing for a growing population; educate talent and attract workforce; manage mobility streams; expanding the energy grid; guard social cohesion; collaborate beyond the region's borders, align permitting procedures and reconsider governance aspects; etc. The Brainport Eindhoven (NL) region is faced with this situation and is eager to learn from regions with similar challenges and experiences within a future Interreg Europe project.